noxious (adjective)

1. The noxious relationship between Bella and Edward in the Twilight saga took a toll on their mental health.

2. According to Greek mythology, Pandora's curiosity led her to open a noxious box, releasing all the evils into the world.

3. In the psychological thriller film 'Black Swan', the protagonist's pursuit of perfection becomes noxious to her mental and physical health.

4. The villain's plot in the comic book series 'Batman' involved releasing a noxious gas to harm the citizens of Gotham City.