mental anguish (noun)

1. In the science fiction novel, the protagonist experiences mental anguish as she grapples with existential questions about the nature of reality.

2. The artist expressed the depths of mental anguish through her powerful and emotive paintings.

3. The horror movie depicted scenes of extreme mental anguish, sending chills down the audience's spines.

4. In the romantic novel, the main character's unrequited love leads to prolonged periods of mental anguish.