manic depression (noun)

1. Despite her manic depression, he stayed by her side throughout her highs and lows, proving his unwavering love for her.

2. The main character in the anime series battled with her manic depression while trying to navigate through her tumultuous teenage years.

3. The horror movie portrayed the main character's descent into madness, with her manic depression contributing to the terrifying and dramatic storyline.

4. In ancient Greek mythology, it was believed that the god Apollo inflicted manic depression upon the mortals as punishment for their sins.