debilitative (adjective)

1. The debilitative disease greatly affected the protagonist in the movie, rendering him incapable of performing basic tasks.

2. The evil sorcerer unleashed a debilitative spell, causing the heroes to struggle in their quest to save the kingdom.

3. The lack of accessibility features in the building resulted in a debilitative environment for individuals with disabilities.

4. The debilitative curse placed upon the hero by the gods weakened him, making it nearly impossible for him to defeat his enemies.